Journal: International Journal for Parasitology: Drugs and Drug Resistance

Article Title: Terpenic compounds possess anthelmintic and immunomodulatory properties with potential for controlling equine cyathostomin infections

doi: 10.1016/j.ijpddr.2026.100642

Figure Lengend Snippet: Scatter plots of the association between TNF-α production and the IC 50 values (LDA and LMA) Scatter plots showing the association between TNF-α production percentage (expressed relative to the control) and the IC 50 values obtained in (left) the Larval Development Assay (LDA) and (right) the Larval Migration Assay (LMA) for six terpene compounds (anethole, cinnamaldehyde, menthol, carvacrol, eugenol and thymol). Each point represents the mean IC 50 and TNFα production for a given compound, and horizontal/vertical bars indicate the corresponding confidence intervals. Lower IC 50 values reflect higher antiparasitic potency.

Article Snippet: The cells were then incubated at +37 °C (5% CO 2 ) for 24 h. After incubation, the concentration of TNF-α in the medium for each condition was quantified by ELISA using mouse TNF-α paired antibodies (R and D Systems DY410).

Techniques: Control, Migration

Journal: International Journal for Parasitology: Drugs and Drug Resistance

Article Title: Terpenic compounds possess anthelmintic and immunomodulatory properties with potential for controlling equine cyathostomin infections

doi: 10.1016/j.ijpddr.2026.100642

Figure Lengend Snippet: Anti-inflammatory activity of carvacrol and cinnamaldehyde on equine PBMC Boxplots showing TNF-α concentrations (ng/mL) measured in equine peripheral blood mononuclear cells (PBMCs) exposed to DMSO (0.05%), LPS (125 ng/mL), the combination of DMSO and LPS, carvacrol (5 μg/mL), cinnamaldehyde (5 μg/mL), the combination of either compound with LPS, and the untreated condition (control). Points represent individual replicates from four independent assays. Asterisks indicate significant differences relative to the corresponding control condition (∗ P = 0.01, ∗∗ P < 0.001).

Article Snippet: The cells were then incubated at +37 °C (5% CO 2 ) for 24 h. After incubation, the concentration of TNF-α in the medium for each condition was quantified by ELISA using mouse TNF-α paired antibodies (R and D Systems DY410).

Techniques: Activity Assay, Control

Journal: Data in Brief

Article Title: The Explore2–2022 climate projections dataset for impact studies over France

doi: 10.1016/j.dib.2026.112659

Figure Lengend Snippet: Ensemble matrices displaying the maps of relative differences ( %) in cumulative winter (DJF) (top panel) and summer (JJA) (bottom panel) precipitation at the end of century (H3, 2070–2099) for the RCP 8.5 scenario compared with the 1976–2005 reference period for each of the 17 GCM/RCM pairs in the Explore2–2022 ensemble. The rows correspond to GCMs, the columns to RCMs (ensemble Explore2–2022, data corrected by ADAMONT method). Hatching marks the grid points where the changes are non-significant with respect to the internal variability, according to the method applied in IPCC AR6.

Article Snippet: The eight criteria are the following: • Number of pairs : around ten GCM/RCM pairs had to be selected, resulting in 12 pairs at the end of the selection process; • RCP ( Representative Concentration Pathway ) scenarios availability and consistency: each pair should be available for at least two RCP scenarios: • GCM quality : GCMs must be deemed realistic over Europe, • Balance : maximum number of different RCMs with a balanced distribution in terms of projected changes, • Absence of known errors : GCM/RCM pairs affected by a known error are rejected, • Account for French simulations : simulations carried out by French research institutes should be included, • Physical consistency : couples with physical consistency between GCM and RCM are to be favoured, • Consistent spread : the dispersion of climate change signal from the EURO-CORDEX (EUR 11) ensemble must be preserved.

Techniques: